Sunday, September 27, 2009

The lateral digital flap for Dupuytren's fasciectomy at the proximal interphalangeal joint - A study of 84 consecutive patients.

Authors: Anwar MU, Al Ghazal SK, Boome RS Fasciectomy is the most common operation performed for Dupuytren's disease. However, as the joint contracture increases, issues of skin deficiency following release become significant. For severe or recurrent disease dermafasciectomy is advised, but a digital transposition flap provides a viable alternative without the need for a skin graft for less-severe disease with moderate skin deficiency. A retrospective review identified 84 patients who had undergone this operation. The flap used was proximally based on the midlateral aspect of the finger allowing direct closure of the donor site. Ninety hands with 134 digits were operated on and 83% of the patients had a full correction. About 70% remained fully corrected at 1 year. All flaps were perfo...
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Monday, September 21, 2009

Dupuytren�s disease of the radial side of the hand

Abstract  Dupuytren�s disease with involvement of the radial aspect of the hand is a clinical entity, which affects the thumb, the first web space, and the index finger. It can be primary or secondary. The palmar fascia anatomy and the clinical aspects of radial Dupuytren�s disease are described. The authors propose a new classification, which has the advantage in requiring only a clinical evaluation. One hundred and fifteen patients were examined for Dupuytren�s disease with radial involvement, primary or secondary, in the Hand Surgery Unit of the University of Modena between 1985 and 1994. Eighty-two (68.3%) of them were treated surgically as hand function was compromised by first web retraction. The most commonly used incisions of the first commissure are straight-l...

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Guillaume Dupuytren (1777-1835) and his contracture

(Source: Journal of Medical Biography)

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FDA gives priority review to Auxilium�s Xiaflex

The Food and Drug Administration granted priority review status to a new drug application filed by Auxilium Pharmaceuticals Inc. for Xiaflex, an experimental treatment for Dupuytren�s contracture. (AUXL) (Source: bizjournals.com Health Care:Health Insurance headlines)

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Friday, September 18, 2009

Injectable collagenase clostridium histolyticum for Dupuytren's contracture

In this study the authors sought to evaluate injection of collagenase clostridium histolyticum into the affected cord as a potential non-surgical option; in previous single-centre studies this has been shown to reduce contractures (works by lysing collagen).    A total ... (Source: NeLM - News)
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FDA gives priority review to Auxilium�s Xiaflex

The Food and Drug Administration granted priority review status to a new drug application filed by Auxilium Pharmaceuticals Inc. for Xiaflex, an experimental treatment for Dupuytren�s contracture. (AUXL) (Source: bizjournals.com Health Care:Industry Regulation headlines)
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Collagenase Injections Can Improve Range of Motion

Injection of collagenase clostridium histolyticum into the affected hand joints of patients with Dupuytren's disease can reduce joint contracture, improve range of motion, and provide an office-based alternative to risky hand surgery, according to a study in the Sept. 3 issue of the New England Journal of Medicine. (Source: Modern Medicine)
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Curved Penis Cures and Remedies

Peyronie's disease is a condition in which a plaque (a thickened, hardened piece of tissue) forms on one side of the penis. If the plaque becomes large enough, it reduces flexibility of the pe...
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